Cytological changes in chlorhexidine-resistant isolates of Pseudomonas stutzeri

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Biology of Pseudomonas stutzeri.

Pseudomonas stutzeri is a nonfluorescent denitrifying bacterium widely distributed in the environment, and it has also been isolated as an opportunistic pathogen from humans. Over the past 15 years, much progress has been made in elucidating the taxonomy of this diverse taxonomical group, demonstrating the clonality of its populations. The species has received much attention because of its part...

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Isolation of chlorhexidine-resistant Pseudomonas aeruginosa from clinical lesions.

The chlorhexidine resistance of 317 strains of Pseudomonas aeruginosa isolated from hospital patients was determined. The distribution pattern of their susceptibility to chlorhexidine clearly revealed two peaks, and the frequency of resistance to chlorhexidine was 84.2%.

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Effects of chlorhexidine diacetate on P. stutzeri ultrastructure

Electron microscopy (EM) is a useful tool for detailed ultrastructural analysis of microorganisms. Both scanning electron microscopy (SEM) and transmission electron microscopy (TEM), which provide information about surface and intracellular changes, can be used for studying the effects of antimicrobial agents on microorganisms. EM has previously been used to study the ultrastructural basis of t...

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Carbapenem and Fluoroquinolone Resistance in Multidrug Resistant Pseudomonas aeruginosa Isolates from Al-Zahra Hospital, Isfahan, Iran

Introduction: The major resistance mechanisms of Pseudomonas aeruginosa to fluoroquinolones and carbapenems are associated with the mutations in the genes gyrA and oprD encoding type II topoisomerases (DNA gyrase) and OprD porin, respectively. Method: In this cross-sectional study, sixty five clinical samples were collected from patients hospitalized in Al-Zahra Hospital of Isfahan, Iran. Susce...

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Ultrastructural study of polymyxin-resistant isolates of Pseudomonas aeruginosa.

Upon exposure to 6,000 U of polymyxin B sulfate per ml, cells of the polymyxin-sensitive PAO 1 strain of Pseudomonas aeruginosa displayed in thin sections long projections arising from the outer membrane of the cell wall and extensive cytoplasmic degradation with accumulation of cytoplasmic membrane infoldings. Polymyxin-resistant isolates derived from the PAO 1 strain, however, grew well in th...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2000

ISSN: 1460-2091,0305-7453

DOI: 10.1093/jac/45.2.145